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You review a 78-year-old man at your GP surgery. His daughte…

Posted byAnonymous July 1, 2021January 9, 2023

Questions

Yоu review а 78-yeаr-оld mаn at yоur GP surgery. His daughter reports a stepwise deterioration in his memory and ability to look after himself and is worried he has Alzheimer's disease. His PMH includes a transient ischaemic attack (TIA) last year and hypertension. He smokes 10 cigarettes per day and receives a hydroxocobalamin injection every 3 months for vitamin B12 Blood pressure is 180/75 mmHg. His neurological examination is unremarkable. He scores 8/30 on the mini-mental state examination (MMSE) with relative preservation of short-term memory. A CT head shows small vessel disease only. Routine bloods are normal except; chronically raised potassium (5.2 mmol/L) which has been extensively investigated and no cause found. A blood vitamin B12 level is 205 μg/mL (normal range 200 μg/mL - 500 μg/mL). Which of the following as a pharmacist would you consider as the MOST appropriate treatment option with regard to his cognitive impairment?

Yоu review а 78-yeаr-оld mаn at yоur GP surgery. His daughter reports a stepwise deterioration in his memory and ability to look after himself and is worried he has Alzheimer's disease. His PMH includes a transient ischaemic attack (TIA) last year and hypertension. He smokes 10 cigarettes per day and receives a hydroxocobalamin injection every 3 months for vitamin B12 Blood pressure is 180/75 mmHg. His neurological examination is unremarkable. He scores 8/30 on the mini-mental state examination (MMSE) with relative preservation of short-term memory. A CT head shows small vessel disease only. Routine bloods are normal except; chronically raised potassium (5.2 mmol/L) which has been extensively investigated and no cause found. A blood vitamin B12 level is 205 μg/mL (normal range 200 μg/mL - 500 μg/mL). Which of the following as a pharmacist would you consider as the MOST appropriate treatment option with regard to his cognitive impairment?

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