Fоr eаch оf the fоllowing mutаtions, indicаte whether the mutation would likely promote (P) or inhibit (I) apoptosis in cells harboring the mutation(s). Your answer should be a four-letter string consisting of "P" and "I" only (e.g., PPPI). A mutation in the pro-apoptotic effector Bcl2 family proteins Bax and Bak that prevents their association with the outer mitochondrial membrane. A mutation in the BIR domain of the IAP protein DIAP1 that prevents binding to either caspases or anti-IAP proteins. A mutation in the anti-IAP protein Reaper that prevents its binding to IAP proteins. A mutation in the CARD domain of caspase-9 that prevents its binding to Apaf1.