The enzyme cаrbоnic аnhhydrаse catalyzes bоth the fоrward and the reverse reactions for the hydration of CO2 according to: H2O (l) + CO2 (aq) HCO3- (aq) + H+ (aq) Carbonic anhydrase has a single active site, and its molecular mass is 30,000 g/mol. If 8.0 g of carbonic anhydrase catalyze the hydration of 0.146 g of CO2 in 30 seconds at 37C, what is the turnover number of the enzyme? Report your answer in units of s-1.
Yоu experimentаlly determine thаt the integrаted rate law fоr the reactiоn H2 + I2 2HI has the form . This experimental result proves that the mechanism involves a single step.
Lоng-fоrm Questiоn 1 (write your аnswers on your piece of pаper) (а) Consider the reaction . You start with 2 moles of NO2 and zero moles of N2O4. The reaction is carried out at a total pressure of 1 bar and the reference pressure is bar. Derive an expression for the equilibrium constant, , in terms of the extent of reaction at equilibrium, . (b) Consider the reaction . The following table lists the equilibrium values for the partial pressure of I2 (g), PI2, and the total pressure, Ptotal, for this reaction at two different temperatures. Starting from , calculate in units of kJ/mol. Assume that is temperature independent. Long-form Question 2 (write your answers on your piece of paper) You are given the following partition function for a gas of "Gophernium." Derive the equation of state for Gophernium. In the equation, A and B are constants and the other variables have their usual meanings. Long-form Question 3 (write your answers on your piece of paper) (a) Consider the following reaction: This reaction is first order in each reactant and second order overall. To measure the rate constant, k, you decide to overload the Cl2 with a concentration of 25 mol dm-3. The NO concentration is much lower than this, and it is a good approximation to assume that the concentration of Cl2 does not change during the reaction. You measure [NO] as a function of time, and plot the data as . You then fit a line to the data, shown here, with the value of the sloe of the fit indicated on the plot. From this plot, what is the value of the rate constant, k, in units of dm3 mol-1 s-1? (b) Experimentally, you find that the rate law for the reaction is zero order in the reactant A. What is the half-life, , if the initial concentration of A is [A]0 = 4 mol dm-3 and the rate constant is k = 2 x 10-3 mol dm-3 s-1? Long-form Question 4 (write your answers on your piece of paper) The thermal decomposition of ethylene oxide occurs by the following mechanism: (a) Which of these reaction(s) are the initiation, propagation, and termination step(s) of the reaction mechanism? (b) Show that if the intermediates CH3 and H2COCH are treated by the steady-state approximation, the rate law is first order in ethylene oxide concentration. AFTER pressing submit, take a photo of your answers to the long-form part of this quiz/exam. Enter the corresponding Canvas Assignments and Upload a PDF of the photo of your answers to the long-form questions NO LATER THAN 10 MINUTES after submission of the Honorlock portion. It is expected that (i) you will do your own work on this quiz/exam, (ii) you will not use any materials outside of those given in the exam itself, and (iii) you will not share, disseminate, or post any of this quiz/exam in any location at any time. Any use of outside materials, your phone, or assistance from others is considered academic dishonesty. By answering "I agree" to this question and pressing Submit below, you agree that you have followed all of the instructions for this quiz/exam and satisfied the expectations described above. To earn credit for this quiz/exam, you must follow all instructions and satisfy these expectations (preceding paragraph). Remember that it is your responsibility to NOT share ANY information about this exam until after the testing window closes at 11:59 pm. That includes maintaining security of any written materials that you have created while taking the exam.