DISOPYRAMIDE Rаtiоnаle Prоvide а ratiоnale utilizing only equations and arrows for your responses in the 'Carbamazepine' question. Table 1A: Steady-state concentrations of disopyramide following intravenous infusions. Disopyramide is a low extraction drug equally eliminated by the kidney and liver. It is 82% bound to plasma proteins. Infusion rate (mg/min) Steady-state concentration (mg/L) 0.08 0.82 0.16 1.3 0.32 2.3