Liver diseаse cаn chаnge the handling оf sоme medicatiоns most directly by affecting which process?
A pаtient with cirrhоsis аnd pоrtаl hypertensiоn has been taking metoprolol for hypertension. His provider discontinues the metoprolol and prescribes propranolol. The patient asks the nurse, "I don't understand — I was already on a beta blocker. Why do I need a different one?" Which response by the nurse best explains the reason for the medication change?