Select TWO structures thаt аre visible/lоcаted in the secоnd layer оf the foot.
Sectiоn C - Pаthоphysiоlogy You only need to аnswer one of the three questions from this section. One аnswer box will be beneath this box - please indicate which question you are answering, for example: 'My Answer to Question X is...' Questions are as followed: Question 6 Prediabetes is metabolic state that predisposes to the development of type 2 diabetes. Describe the major pathological mechanisms underpinning the development of prediabetes and progression to type 2 diabetes? Answers should make reference to the impact of prediabetes glucose-phenotypes. (100%) Question 7 Discuss the current treatments options for Parkinson’s disease and their role in the clinical management of the condition (100%) Question 8 A patient has entered the Emergency department with chest pain. The pain has been described as a burning pain in the centre of the chest that has been constant for the last hour. The patient has tried three attempts at easing the pain with GTN spray and when they did not resolve the pain he contacted emergency services as directed by his doctor. The 12 lead ECG performed in the Emergency department shows widespread concave ST elevation in leads V1-V4. A diagnosis of ST elevation myocardial infarction (STEMI) is made and the patient is referred for emergency percutaneous coronary intervention (PCI) . Please answer all parts of the question below. a) Explain the underlying pathophysiological mechanisms and the timeline of events that occur within the coronary arteries that lead to the patient experiencing an ST elevation myocardial infarction (STEMI). As part of your answer include an explanation of the role of serum cholesterol in the underlying pathophysiology of this condition. (60%) b) What is the purpose of performing a 12 lead ECG in patients with suspected ST elevation myocardial infarction and what is the significance of the ST elevation? As part of your answer you should highlight the difference in the presentation of STEMI, compared with other forms of coronary artery disease. (20%) c) What is the significance of the failure of the GTN spray to ease the patient’s symptoms? (20%)