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Posted byAnonymous October 2, 2026October 2, 2026

Questions

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Mr Thembа Mоkоenа, а 64-year-оld man with a long smoking history and diagnosed with an obstructive disease, attends a preoperative assessment before elective hernia repair. He reports progressive breathlessness and a persistent cough. At rest, he breathes rapidly with a reduced tidal volume and has prolonged expiration. Pulmonary function testing produces the following results:       Measurement & ResultTotal lung capacity (TLC):  Within the normal rangeResidual volume (RV): IncreasedFEV₁: ReducedPost-bronchodilator FEV₁/FVC: 55%Arterial   PO₂ (on room air): 55   mmHg (reference: 80–100 mmHg)Arterial   PCO₂ (on room air): 55   mmHg (reference: 35–45 mmHg)Identify TWO blood-gas changes that could stimulate Mr Mokoena’s increased respiratory drive. For each abnormality, explain how it stimulates increased respiratory drive through the relevant chemoreceptors.                                                  [BLANK-1]       

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