A 29-year-old woman with moderate persistent asthma is taking an inhaled corticosteroid and is being considered for add-on salmeterol. She asks why she cannot simply use her albuterol inhaler more frequently. What best distinguishes salmeterol from albuterol in this context?

 A 13-month-old develops fever of 103°F and a rash 9 days after their Varicella vaccination. The caregiver is concerned about febrile seizures and long-term neurologic risk. Which of the following statements is true? 

A 64-year-old patient receiving myelosuppressive chemotherapy has a platelet count of 38,000/µL and reports bone pain from metastases. The provider is considering an NSAID adjunct. Which option is safest regarding platelet effects?

A 52-year-old man with severe asthma is transitioning from a 3-week course of oral prednisone to maintenance inhaled fluticasone. What is the most important safety consideration during this transition?

A 59-year-old patient with metastatic lung cancer reports constant pain rated 7/10 despite trying acetaminophen at home. Which initial pharmacologic approach is most appropriate?

A 37-year-old patient presents with fatigue and low-grade fever after recent travel. Serologic testing for hepatitis A reveals positive anti–HAV IgG and negative anti–HAV IgM. Which interpretation of these results is most appropriate?

A 71-year-old woman with stage 3 chronic kidney disease develops constipation while receiving opioid therapy after surgery. Which laxative should be avoided?

A 78-year-old man with GERD and a seizure disorder treated with phenytoin is taking cimetidine for heartburn. His phenytoin levels are now supratherapeutic despite no dose changes. What best explains this finding and the most appropriate management?

A 29-year-old with frequent migraines asks about monthly injection options for prevention. Which therapy is most consistent with a monoclonal antibody approach?

A 67-year-old patient with coronary artery disease and a history of myocardial infarction takes aspirin 81 mg daily for secondary prevention. The patient is scheduled for elective cataract surgery and asks when the aspirin should be stopped to prevent bleeding. What is the most appropriate recommendation?