A 38-year-old woman with primary adrenal insufficiency recei…
A 38-year-old woman with primary adrenal insufficiency receives oral hydrocortisone 20 mg in the morning and 10 mg in the afternoon. Despite adherence, she reports insomnia, weight gain and increased appetite. Her afternoon hydrocortisone dose is taken at 20:00. Which pharmacological intervention is most appropriate?
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