Which neurotransmitter systems are most commonly implicated in the pathophysiology of major depressive disorder?

Which drug requires slow titration to avoid risk of severe rash?

Use Simpson’s Rule and n = 6 to find an approximation for the definite integral

A 45-year-old man with schizophrenia taking clozapine for 8 months presents with fever and sore throat. His WBC is 2,500/µL and ANC is 900/µL. What should the ARNP do next?

A 33-year-old woman with bipolar II disorder is prescribed a medication that is particularly effective for preventing bipolar depression and works by inhibiting glutamate release and blocking voltage-sensitive sodium channels. Known by the brand name, Lamictal.  Which drug has this mechanism of action?

Atypical antipsychotics are often used in bipolar disorder. Which of the following is FDA-approved for bipolar depression?

Which antidepressant carries the highest risk of inducing a switch to mania in a patient with bipolar disorder?

A 45-year-old man on long-term clozapine therapy presents for routine monitoring. Which lab value must be checked regularly to prevent a life-threatening adverse effect?

A 14-year-old boy with new-onset schizophrenia is started on pharmacologic therapy. Which agent is FDA-approved for this age group?

A 29-year-old pregnant woman (16 weeks gestation) has schizophrenia controlled on haloperidol. She asks whether she should stop it. What should you recommend?