Regulation of hormone activity.

Compare/contrast endocrine glands.

Endocrine anatomy.

Endocrine secretion.

Regulation of hormone secretion

Achondroplasia is a form of dwarfism that shows autosomal dominant inheritance, with the homozygous dominant genotype being lethal before birth. If a couple with Achondroplasia have a live birth, what is the probability the child will have the unaffected phenotype? 

Spinal muscular atrophy (SMA) type I shows autosomal recessive inheritance. Assuming complete penetrance, if two heterozygous individuals have a child, what is the probability the child will be affected with SMA type I?  

Melanin synthesis (which produces pigment) in the eye is determined by 2 genes. The OCA2 gene controls melanin synthesis; MM or Mm = brown color; mm = blue color The HERC2 gene controls (“switches on”) the OCA2 gene; HH or Hh = brown color; hh = blue color. Therefore, a homozygous recessive genotype for either gene (i.e., hh or mm) results in blue eyes. Two parents, one with blue eyes and one with brown eyes, have the following genotypes: hhmm and HhMm . What is the probability that they will have a blue-eyed child?  (Use the forked-line method or do a Punnet square).

The blood type A allele (IA) and blood type B allele (IB) are both completely dominant over the blood type O allele (i). The Blood type A allele and blood type B allele are codominant. A woman is blood type B and has 3 children with a partner of unknown blood type. One child is blood type A and 2 children are blood type O.  What is the probability that child number 4 will be blood type B?

Spinal muscular atrophy (SMA) type I shows autosomal recessive inheritance. Assuming complete penetrance, if two heterozygous individuals have two children, what is the probability that the first child will be unaffected and the second child will be unaffected?