In 1953, Watson and Crick published a discovery without doing a single laboratory experiment. Finally, Watson and Crick used a recently proposed concept from Linus Pauling. Which idea that Pauling proposed about protein structure did Watson and Crick use? How did Watson and Crick use Pauling’s concept and Chargaff’s and Franklin’s data to come up with their discovery?

Which level of protein structure is described when one describes how sections of stereotypical structures are connected? _______

Which cellular form of DNA is left-handed? _______

What is the name of the bond that holds two DNA polymeric strands to each other? _______

What are two specific examples of non-coding DNA found in genes?

What is the term that refers to the temperature at which 50% of DNA in solution is denatured? _______

View figure 2 versus 3. Why are the heavy ribosomes labeled with P-32? Besides being labeled with P-32, how do you know these ribosomes are not light? (Ribosomes made in nutrient broth would have N-14 and C-12 isotopes. But, this is not how you know which band has light and which band has heavy ribosomes.) What did the authors want to control for with this experiment?

Hemostasis is achieved by all of the following EXCEPT:

What was the controversy that the authors wanted to address?

View Figure 4. Labeled RNA (intermediate carrier) associates with band B. Is band B intact ribosome or ribosomal subunits? What happens to the radioactive peak when one decreases the size of band B with low Mg2+ concentration?