The patient was prescribed prednisone which is a synthetic f…
The patient was prescribed prednisone which is a synthetic form of cortisol, a lipid soluble hormone. Identify three differences between lipid soluble hormones and water soluble hormones. NOTE: You do not need any information from the case study to answer this question.
Read DetailsAfter 12 months of treatment scans confirmed that she was in…
After 12 months of treatment scans confirmed that she was in remission and there was no evidence of abnormal lymphocytes. However, six months later at a follow up appointment the patient complained of bone pain in her hips and sternum and her oncologist noticed swollen lymph nodes and ordered a biopsy, CBC, and PET scan. The blood tests identified an abnormally high number of circulating antibodies in the blood and a high blood viscosity (thickness) as a result. The results of the remaining tests confirmed this and resulted in a diagnosis of chronic lymphocytic leukemia, a blood cancer that results in slow progressing excess lymphocyte proliferation. This is a rare but not uncommon side effect of the drugs meant to treat the lymphoma. The doctor ordered plasmapheresis to treat the high blood viscosity and decided to begin her on a course of treatment involving brentuximab, a monoclonal antibody therapy. Name and describe three ways that circulating antibodies target foreign invaders for elimination.
Read DetailsReed-Sternberg cells (RSCs) are large multi-nucleated lympho…
Reed-Sternberg cells (RSCs) are large multi-nucleated lymphoid cells. They result from a specific cell type that grows but fails to completely divide, differentiate, or act normally. The presence of RSCs results in a reduced number of antibodies in the blood but does not affect cells that trigger apoptosis. Based on this information, what line of cells give rise to RSCs and why did you choose that answer?
Read DetailsQuestion 4 — Lab data: the missing force (20 points) Student…
Question 4 — Lab data: the missing force (20 points) Students connect a cart on a level track to a hanging mass using a light string over a pulley. They release both from rest, record the cart’s velocity, and use the slope of each velocity–time graph to find the acceleration. Their first calculation assumes no friction and an ideal string and pulley. For a control test, they disconnect the string and hanging mass, give the 1.20 kg cart a push to the right, and record how it slows on the same track. The other cart mass is 1.80 kg. Use g = 9.80 m/s². Take right for the cart and down for the hanging mass as positive. Main trials Trial Cart mass (kg) Hanging mass (kg) Measured acceleration (m/s²) A 1.20 0.240 0.63 B 1.20 0.360 1.34 C 1.20 0.480 1.94 D 1.80 0.240 0.09 E 1.80 0.480 1.12 Selected sensor readings Time (s) Trial A velocity (m/s) Coast-down velocity (m/s) 0.00 0.000 1.80 0.50 0.315 1.20 1.00 0.630 0.60 1.50 0.945 0.00 Show your work: Draw free-body diagrams for the connected cart and hanging mass, including a force the initial calculation may have overlooked. Also draw a force diagram for the cart during the disconnected coast-down test. (3 pts) Use the raw velocity readings to determine the acceleration in Trial A and in the coast-down test. Explain the sign of each slope. (2 pts) Write Newton’s second law for both connected masses and derive the frictionless acceleration equation. Calculate predictions for Trials A and D; compare with measured acceleration. (3 pts) Use the coast-down result to estimate the resistive force on the 1.20 kg cart and its kinetic friction coefficient. State the assumption needed to apply that coefficient to the 1.80 kg cart. (3 pts) Include friction in the system equation. Recalculate the expected acceleration for Trials A and D, and compare with the measurements. (3 pts) What did the original model leave out? Support your explanation with three numerical observations, including one from the coast-down test. Give another possible explanation that the data do not fully eliminate. (4 pts) Describe a follow-up experiment that would distinguish your explanation from the alternative. State what you would change, control, measure, and expect to observe. (2 pts) Upload ONE PDF at the end of the exam containing all of your written solutions. Do not upload a separate file for this question.
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