A 39-year-old woman returns to the office 2 weeks after starting levothyroxine for newly diagnosed primary hypothyroidism. She reports that she “doesn’t feel much different yet” and asks whether the medication is working.Which response by the nurse practitioner is most appropriate?

A 38-year-old woman is diagnosed with iron deficiency anemia secondary to heavy menstrual bleeding. She asks how she should take her iron supplement to improve absorption.Which of the following instructions is most appropriate?

A 35-year-old healthy woman experiences heartburn approximately twice per month after eating spicy foods. Symptoms resolve within an hour, and she denies dysphagia, weight loss, anemia, or nocturnal symptoms. Which medication is the most appropriate first-line pharmacologic treatment?

A 57-year-old woman is found to have a 1.8-cm thyroid nodule during a routine examination. She denies dysphagia or hoarseness. Her TSH is within the normal reference range. What is the next best step in evaluating this patient?

A 72-year-old man with hypertension and type 2 diabetes returns for follow-up after being diagnosed with Stage 3a chronic kidney disease six months ago. At the time of diagnosis, his laboratory studies revealed an eGFR of 52 mL/min/1.73 m² and a UACR of 180 mg/g. Today, he reports feeling well and denies urinary symptoms. His blood pressure is well controlled on lisinopril, and his diabetes is stable. Which of the following is the most appropriate follow-up plan for monitoring his kidney disease?

A 42-year-old man presents for a wellness examination. His lipid panel reveals an LDL cholesterol of 212 mg/dL, HDL cholesterol of 42 mg/dL, triglycerides of 168 mg/dL, and total cholesterol of 298 mg/dL. He has no history of ASCVD, diabetes, or hypertension. What is the most appropriate initial management?

An asymptomatic patient is found to have bacteriuria on a urine dipstick. Antibiotic therapy is appropriate if the patient:

A 34-year-old otherwise healthy woman presents to your primary care office with a 2-day history of dysuria, urinary urgency, and urinary frequency that has progressed to fever, chills, nausea, and left-sided flank pain. She is alert, well hydrated, and able to tolerate oral fluids. Vital signs are as follows: temperature 100.8°F, blood pressure 118/72 mmHg, heart rate 92 bpm, respiratory rate 16 breaths/min, and oxygen saturation 99% on room air. Physical examination demonstrates left costovertebral angle tenderness. Urinalysis reveals positive nitrites, positive leukocyte esterase, pyuria, bacteriuria, and WBC casts. A urine culture is obtained before initiating treatment. Which of the following is the most appropriate antibiotic selection?

A 40-year-old woman is newly diagnosed with hyperthyroidism. During the visit she asks whether her eye irritation and “bulging eyes” are related to her thyroid condition. Which diagnosis best explains these findings?

A 69-year-old man with hypertension and stable coronary artery disease is newly diagnosed with primary hypothyroidism. His calculated full replacement dose is approximately 120 mcg/day. Which initial levothyroxine prescription is most appropriate?