Recalling the term “ADME” … When a drug is administered to a patient, the concentration of the drug in the blood increases, and then falls with time. Question: Select the TWO TERMS terms (A, D, M, or E) that would most likely cause an INCREASE in the concentration of the drug in a patient’s urine…

Caffeine 101: What type of Phase I metabolism could caffeine potentially undergo up to THREE times? [blank1]

Recalling the term “ADME” … When a drug is administered to a patient, the concentration of the drug in the blood increases, and then falls with time. Question: Which of the four terms (A, D, M, or E) would most likely cause an INCREASE in the concentration of the drug in a patient’s blood?

Select the in vitro conditions/parameters that can affect the ability of an enzyme to function properly. (select all that apply)…

Honor Code Statement: “The work on this exam is my own and I pledge to not use any outside resources or people to help me.  By clicking TRUE I pledge that I will not cheat or assist anyone else in cheating”. 

Enzymes and Receptors are similar in the sense that both are composed of: [blank1]

Caffeine 101: Caffeine’s mechanism of action in the body involves binding to and inhibiting the _____ receptor.

The reaction shown here depicts a drug (used in the treatment of overactive bladder) being converted to its active form. As a result of the reaction shown, the product of the reaction is more _____ than the reactant.  

Caffeine 101: Caffeine has a pKa of 14. At pH = [blank1], caffeine will be 90% Ionized

The drug shown here can be used unaltered from its plant (yew tree) derived natural structure to treat cancer. *** The drug contains [blank1] hydrogen bond acceptor (HBA) groups.