A 70-year-old patient presents to the emergency department w…
A 70-year-old patient presents to the emergency department with dizziness, weakness, and confusion after 4 days of profuse vomiting and diarrhea. On examination, the patient is hypotensive with orthostatic changes, tachycardic, and has dry mucous membranes. Laboratory results reveal the following: Sodium: 124 mEq/L Serum osmolality: low Urine sodium:
Read DetailsA 56-year-old man presents to the acute care clinic with pro…
A 56-year-old man presents to the acute care clinic with progressive fatigue, early satiety, and a 12-pound unintentional weight loss over the past 3 months. He also reports intermittent night sweats but denies recent infections. Physical examination reveals marked splenomegaly. A peripheral blood smear demonstrates numerous mature granulocytes with myelocytes and metamyelocytes, with 2% blasts. Laboratory Test Patient Value Reference Range CBC WBC 182,000/µL 4,000–11,000/µL Hemoglobin 13.8 g/dL 13.5–17.5 g/dL Hematocrit 41% 41–53% Platelets 610,000/µL 150,000–400,000/µL Peripheral Blasts 2% 0% Chemistry Vitamin B12 2,450 pg/mL 200–900 pg/mL LDH 620 U/L 140–280 U/L Uric Acid 9.8 mg/dL 3.5–7.2 mg/dL Diagnostic Studies BCR-ABL (PCR) Positive Negative Philadelphia Chromosome Present Absent Which of the following is the most likely diagnosis?
Read Details*Bonus Question* 2 points will be added to the final exam gr…
*Bonus Question* 2 points will be added to the final exam grade if answered correctly. No penalty for incorrect answers. A 58-year-old patient with a newly diagnosed brain tumor is admitted to the ICU. He develops severe cerebral salt wasting with a serum sodium level of 111 mEq/L. He is started on 3% saline with frequent monitoring of serum sodium levels. During treatment, the patient’s serum sodium increases to 123 mEq/L within 24 hours. Which of the following complications is the patient at risk for?
Read DetailsA 67-year-old patient is admitted after a gastrointestinal h…
A 67-year-old patient is admitted after a gastrointestinal hemorrhage with ongoing melena and hypotension. Despite receiving intravenous fluids, the patient remains tachycardic with a blood pressure of 86/54 mmHg. Laboratory results show a hemoglobin of 7.2 g/dL. The Adult-Gerontology Acute Care Nurse Practitioner (AGACNP) initiates measures to control the bleeding and consults gastroenterology for urgent endoscopy. Which of the following is the most appropriate next step in management of this patient’s acute blood loss anemia?
Read DetailsA 68-year-old man is admitted to the cardiac intensive care…
A 68-year-old man is admitted to the cardiac intensive care unit following an inferior ST-elevation myocardial infarction (STEMI). He underwent successful percutaneous coronary intervention (PCI) with placement of a drug-eluting stent to the right coronary artery (RCA). Prior to transfer from a rural critical access hospital, he was started on an intravenous unfractionated heparin infusion. On post-procedure day 1, you review his laboratory results and note that his platelet count has decreased to 70,000/µL. Review of records from the referring facility reveals his platelet count was 320,000/µL before initiation of heparin therapy. Which of the following diagnostic tests is the most appropriate next step?
Read DetailsA 42-year-old patient with HIV Infection is admitted to the…
A 42-year-old patient with HIV Infection is admitted to the hospital with a painful rash on the right side of the chest. The rash began 3 days ago as tingling and burning pain, followed by the development of erythematous vesicular lesions. Examination reveals a painful erythematous, maculopapular eruption along multiple thoracic dermatomes. Laboratory testing reveals a CD4 count of 280 cells/mm³. Which of the following is the most appropriate management for this patient?
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