Consider the structure of Vitamin D shown here. Select only the TRUE statement(s). (select all that apply…)

Recalling discussions regarding “what’s in a drug name?”, of the functional groups listed below, select the group(s) that are likely to be present in a drug named DIPHENHYDRAMINE? (select all that apply)

What is the correct technique for lifting heavy objects?

Which of the following correctly indicates the relative strengths of attractive forces?

Which of the following is NOT a responsibility of a Respiratory Care Department Manager?

Refer to Drug Y for this question. Determine if the statements regarding Drug Y are either TRUE or FALSE.  

You are now entering the FREE RESPONSE SECTION! There are 6 free response questions (5pts ea).

Consider the figure shown. Hydrogen bonds vary in strength but are typically optimal in [blank1] or “head-on” orientation. (hint: enter a geometric angle, e.g. 50 degrees)

Which of the following is NOT one of the top three causes of death in the United States?

Part1: Consider the structure of the drug NICOTINE and the pKa table shown here.  Drug HA BH+ Nicotine  — N1=3.12 N2=8.02 *** a) Explain the pKa values for N1 and N2. [blank1] (e.g., the pKa for N1 is greater/less than pKa for N2 because…) *** b) At what pH would nicotine be sufficiently protonated to have a total +2 charge? [blank2] (e.g. pH = ##) Part 2: Nicotine (in nicotine gum) is sometimes flavored with artificial sweeteners such as acesulfame, an acidic compound shown here: *** c) The acidic group in acesulfame is a sulfonamide. Which point(s) on the molecule (a-f) include the sulfonamide functional group? [blank3] (e.g. a to b or b to f…) *** d) Assuming nicotine is completely ionized (+2, see b above)…If nicotine and acesulfame reacted to form a salt, what would be the ratio of nicotine to acesulfame? [blank4] (e.g. 2:3 or 2 to 3) Considering either functional group N1 or N2 in nicotine, use the Henderson-Hasselbalch equation to determine the molar ratio and % IONIZED, %UNIONIZED for Nicotine at pH 7.4  Possibly helpful equations:   pH = pKa + log(A-)/(HA)    -or-     pH = pKa + log(B)/(BH+) *** e) Please specify N1 or N2 and then your percentages: [blank5] (e.g. N1: %I = ##.#; %UI = ##.#)