The PHQ – 9 ( Patient Health  Questionaire 9)  Screening tool for depression  utilizes 9  questions to screen patients  for severity of depression.   Those include the following:   Select all that apply 

The  NP  is examining  a 4 month old infant with white coating to tongue and thick  white plaques to buccal mucosa .  Mother reports the infant is bottle fed and feeding well.  What is the most likely diagnosis and effective treatment ? 

Essay. Answer the following within three paragraphs. (10 points)Chapter 11 introduced us to various metrics. Apply lessons and concepts from Chapter 11 in this essay. Recall your BBR or SMM Plan project, and explain how you would measure the effectiveness of a social media campaign. 

Since the 1980s, incarceration has grown ten-fold in the US rising from roughly 200,000 incarcerated in 1980 up to 2.3 million at it’s peak in 2010, mainly attributed to a sharp rise in overall criminality during this time. 

Complete the following paragraph about limb bud anatomy by selecting the correct term for each blank: The developing limb bud can be divided into three functionally distinct regions. The [1] is a structurally distinct ridge of epithelium at the most distal tip of the limb bud that bisects the dorsal and ventral halves; it secretes FGF-8 and is required for limb outgrowth. Directly beneath it is the [2] ,  a mass of proliferating progenitor cells. Restricted to the posterior-most portion of the bud, the [3] is a source of Sonic Hedgehog signaling, and when transplanted to the anterior side of a forelimb bud, causes mirror-image digit duplication.

A patient is diagnosed with a neurocristopathy. Which of the following observations would be consistent with this diagnosis? Select all that apply.

Read the following passage and see the figure below. This is question 2 of 2 about this passage and figure. “The popular herbicide atrazine induces a compound that converts testosterone into estrogen. Researchers wanted to know whether the survival of some amphibian species could be at risk due to atrazine’s effects on the number, function, and fertility of males. In Hayes et al. (2002), researchers tested the hypothesis that atrazine reduces testosterone levels in male frogs by exposing one group of 90 male frogs to 25 parts per billion (ppb) atrazine every 3 days for 46 days. A group of 90 control males and a group of 90 control females were treated identically to the atrazine-treated group, except they were not exposed to atrazine. All frogs were housed individually and fed Purina rabbit chow. After 46 days, individual testosterone levels were measured in frogs from each group. The results are below.”   QUESTION: Identify the researchers’ hypothesis and prediction.

Which of the following statements about Hox genes and anterior-posterior axis specification are correct? Select all that apply.

Felipe is a new graduate student tasked with investigating the following research question: What does the protein IGF-5 do during limb development? To investigate this question, his lab originally tried designing an Igf-5 “knock-out” mouse, in which both Igf-5 alleles were deleted, in hopes of observing whether the limbs were missing or malformed. However, the knock-out mouse did not survive past day 6 of development, which made it impossible to determine how IGF-5 functioned during later stages of development when limbs form. Felipe knows that the protein BRIT-2 inhibits IGF-5, and that BRIT-2 is only expressed later in development (after day 6). Felipe suggests genetically engineering a mouse that overexpresses BRIT-2 (makes more BRIT-2 protein than usual), assuming that it will inhibit IGF-5 during limb development. What type of experimental design is this? (Hint: Felipe’s question is about IGF-5, not BRIT-2)

How is the anterior visceral endoderm (AVE) established in the mouse embryo?