The following is a mechanism of action of efavirenz : (1)1.   Competitive inhibition of the viral reverse transcriptase enzyme      2.   Inhibition of the viral protease enzyme      3.   Inhibition of the viral integrase enzyme                  4.   Inhibition of viral protein synthesis                    5.   Allosteric inhibition of the viral reverse transcriptase enzyme

The following is an adverse effect of naproxen: (1)1.       Weight gain2.       Peptic ulceration3.       Hair loss4.       Pyrexia5.       Hyperthyroidism

Match the following drugs with their correct mechanism of action below. You may use an option more than once or not at all. (5)

Eradication of helicobacter pylori needs the following agents as part of regimen except: (1)1.    Omeprazole2.    Doxycycline3.    Azithromycin4.    Misoprostol5.    Metronidazole

A 22-year old patient who presented with severe lower abdominal pains was diagnosed with endometriosis. One month after being on treatment, she developed virilisation. The possible cause of this adverse effect is: (1)1.    Ibuprofen2.    Diclofenac3.    Paracetamol4.    Danazol5.    Mefenamic acid

The mechanism of action of nevirapine is as follows: (1)1.   It is incorporated into growing viral DNA chain, causing chain termination                                      2.   Inhibits the viral protease enzyme                                                                                                             3.   Inhibit the viral integrase enzyme                                                                                                         4.   Inhibits viral protein synthesis                                                                                                                 5.   Allosteric inhibition of the HIV reverse transcriptase enzyme 

The following drug is an analogue of Prostaglandin E₁: (1)1.    Metronidazole2.    Clarithromycin3.    Amoxicillin4.    Misoprostol5.    Cimetidine

The following drug is classified as a selective Cyclooxygenase (COX-2 inhibitor): (1)1.       Celecoxib2.       Tramadol3.       Morphine4.       Paracetamol5.      Diazepam

A patient with end-stage renal disease may benefit from the use of the following: (1)1.    Ascorbic acid2.    Zinc sulphate3.    Paracetamol4.    Diclofenac5.    Erythropoietin

The following drug may be used in treatment of opioid overdose: (1)1.       Naloxone2.       Carbocisteine3.       Methionine4.       Flumazenil5.       Acetylcysteine