A 53-year-old MtF transgender patient has been on estrogen t…
A 53-year-old MtF transgender patient has been on estrogen therapy for 31 years and underwent surgical gender reaffirmation with construction of a neovagina using scrotal skin flaps 27 years ago. Since her surgery, the patient has engaged in unprotected sex with multiple male partners. She currently presents with a mucopurulent, creamy neovaginal discharge. While inflammation in the lower third of the neovagina is noted during a physical examination, it is otherwise normal. The patient would best be treated with which of the following?
Read DetailsA research study is conducted to examine male infertility. A…
A research study is conducted to examine male infertility. A population of males is identified whose spermatid nuclei are only 10% smaller than their respective spermatogonial stem cells. Which of the following is most likely responsible for reduced DNA condensation of the spermatid nuclei?
Read DetailsA 52-year-old MtF transgender seeks medical attention becaus…
A 52-year-old MtF transgender seeks medical attention because she has noted neovaginal bleeding for the past month. She has been on estrogen therapy for 25 years, underwent breast augmentation 18 years ago and underwent gender re-affirming surgery by orchiectomy, penectomy and penile/scrotal skin flap construction of a neovagina at the age of 39. Upon physical examination, an invasive carcinoma is noted at the apex of the neovagina. Histological examination is most likely to indicate that this lesion is a/an:
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