Double negative thymocytes will initiate rearrangement of which receptor genes first? 

_____ of thymocytes is necessary to produce a T-cell repertoire capable of interacting with self-MHC molecules.

___ are stimulated by cytokines binding to cytokine receptors. This stimulation leads to the phosphorylation and activation of ___.

Which of the following is the least common known lineage of the T-cells?

Negative selection:

Positive selection:

Which of the following receptor genes are the first to be rearranged in a double negative thymocyte?

T-cells go through somatic recombination in the _____________, and T-cells differentiate into effector cells in the ___________.

Which of the following can be found in the thymus?

Effector T cell homing to inflamed tissue is facilitated by _________ expression on the effector T cell surface.