The two most common lineages of T-cells, α:β and μ:δ T-cells, develop in parallel from common precursors.

The pre-TCR complex is composed of a functional α chain, a surrogate β chain (preTβ), CD3 proteins and ζ chain.

Upon recognition of pathogen via innate immune receptors, what co-stimulatory molecule does a dendritic cell start expressing that allows it to activate naive T-cells?

Sphingosine 1-phosphate directs naive T-cells out of the lymph node back into the lymph.

T-cells are activated in the _______ and T-cell maturation takes place in the _______?

A thymectomy of a 25 year old male will result in:

Which of the following is false about TH2 cells?

When would you expect to see RAG-1 and RAG-2 expressed during the process of T-cell development?

AIRE (autoimmune regulator) is used by a subpopulation of thymic epithelial cells during positive selection to produce some peripheral self peptides.

Langerhans’ cells are a type of mature dendritic cells that take up antigens when the skin is breached.