Suppose you are a drug researcher studying this pathway. Choose one of the proteins in the signaling pathway, and propose a hypothetical drug (let’s call it Drug H) that would reduce proliferation in these cells. Say why you chose this protein to target, and explain briefly: What do you want the drug to do to this protein, in terms of 1) its affinity and 2) its efficacy? 3) How will this drug affect the other proteins in the pathway, and what is the ultimate result on the cell?

The following figure is from Research Paper #1. In a few sentences each, explain: 1) Why were K562 cells used in this study? 2) Why would the drug cause an increase in benzidine positive cells? 3) What is the major point this figure makes? (Why did the authors do this experiment?)

In this signaling pathway, kinases 1-3 are acting as:

Teachers will hand grade for spelling errors that cause the answer to be marked wrong. Your final grade after the test may change once the teacher checks for errors.  For example: if you write nucleus as nuclei, the computer will not give you credit automatically.

1 bonus point What tools do you find most helpful in completing the assignments and preparing for the exams?

Teachers will hand grade for spelling errors that cause the answer to be marked wrong. Your final grade after the test may change once the teacher checks for errors.  For example, if you write nucleus as nuclei, the computer will not give you credit automatically.

Why do we call macronutrients “macro”? 

To maintain our physical wellness, we should _____________ bad habits like smoking. 

Why should we limit our consumption of excess saturated fats like butter, ghee, fatty meats? Choose the 2 that apply. 

A management consulting firm recommends that the ratio of middle-management salaries to management trainee salaries be 6:5. Using this recommendation, what is the annual middle-management salary if the annual management trainee salary is $17,000? (Round your answer to the nearest dollar.) Answer: $____