You have identified a molecule, molecule X, that can bind to…
You have identified a molecule, molecule X, that can bind to the ATP binding site of a specific protein kinase, and prevent ATP binding. You are conducting a kinase assay using this protein kinase and a known substrate of this kinase, and have set up the reaction using the proper conditions and cofactors to allow for optimal protein kinase activity. If you add molecule X to the reaction, what do you predict will be the outcome?
Read DetailsA researcher is working to generate a new cancer drug. Thus…
A researcher is working to generate a new cancer drug. Thus far, he has identified a compound that can reduce the size of tumors in the lung. However, in order for the drug to work, the lung tumor has to be small. In addition, the tumor cannot have metastasized (spread to other areas of the body). Furthermore, he knows that the drug acts to prohibit the signaling from one tumor cell to another tumor cell. Given the above information, this new drug prohibits:
Read DetailsThe drug Taxol, or Paclitaxel, is used to treat patients wit…
The drug Taxol, or Paclitaxel, is used to treat patients with a variety of cancers, including breast, lung and ovarian cancers. The drug works by stabilizing microtubules, and preventing their disassembly. The goal of this drug is to prevent dividing cells from completing mitosis. As a result, cancerous cells can no longer divide. In a cell treated with Taxol, at what stage of mitosis will the cells arrest?
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