A 62-year-old male presents for follow-up two weeks after ho…
A 62-year-old male presents for follow-up two weeks after hospitalization for an ST-elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention and drug-eluting stent placement. His current medications include aspirin, atorvastatin 80 mg daily, and metoprolol succinate 50 mg daily. Blood pressure is 128/76 mm Hg, heart rate 64 bpm, and LVEF is 38%. Which of the following medications should be initiated to reduce mortality and prevent adverse ventricular remodeling?
Read DetailsJT is a 48 yo with a history of gastrointestinal bleed, hype…
JT is a 48 yo with a history of gastrointestinal bleed, hypertension, hyperlipidemia, type II diabetes mellitus, and obesity. He presents to the clinic for pain management for his hip osteoarthritis. He has tried acetaminophen and topical Voltaren (diclofenac) for the past six months and he is receiving no relief. It was determined that his cardiovascular risk profile is too high to consider a Cox-2 inhibitor. Which of the following NSAIDS would present the lowest risk of gastrointestinal adverse events for JT?
Read DetailsA 71-year-old female with severe COPD (FEV₁ 38% predicted) p…
A 71-year-old female with severe COPD (FEV₁ 38% predicted) presents for follow-up. She has chronic bronchitis symptoms and reports two hospitalizations for COPD exacerbations in the past year despite adherence to triple inhaler therapy (fluticasone/umeclidinium/vilanterol). She quit smoking 3 years ago. FEV 1= 42%. Blood eosinophil count is 90 cells/µL. She denies asthma history. Oxygen saturation is 93% on room air. BMI is 21 kg/m². Which of the following is the most appropriate next step in pharmacologic management?
Read DetailsA 50-year-old woman presents with joint pain, swelling, and…
A 50-year-old woman presents with joint pain, swelling, and morning stiffness lasting more than an hour. She has tenderness and synovitis in multiple joints, including the wrists and small joints of the hands. Laboratory tests reveal positive rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP) antibodies. Her erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are elevated. Radiographs show early erosive changes in the metacarpophalangeal joints. Which of the following is the most appropriate initial pharmacological treatment for this patient?
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