A client has been taking a proton pump inhibitor (PPI) such as esomeprazole or omeprazole daily for several years. Which findings should the nurse recognize as potential long-term adverse effects of PPI therapy? (Select all that apply.)  (Select all that apply.)

A client beginning a chemotherapy regimen with a high risk of delayed nausea and vomiting is prescribed aprepitant in addition to ondansetron. The nurse should recognize that aprepitant works by which mechanism?

A client preparing for a cruise asks the nurse when to take meclizine (Antivert) to prevent motion sickness. Which response is correct?

A client asks the nurse why famotidine was prescribed instead of omeprazole for mild, occasional heartburn. Which explanation best reflects appropriate clinical reasoning?

A nurse is reviewing a client’s cardiac history before administering IV ondansetron (Zofran) for postoperative nausea. Which finding is most important to report to the provider before giving this medication?

A client is prescribed sucralfate for a duodenal ulcer, along with an antacid for breakthrough discomfort and levothyroxine for hypothyroidism. How should the nurse schedule these medications?

A nurse is teaching a client about prochlorperazine. Which adverse effects should the nurse include in the teaching? Select Yes (if expected) or No (if not expected) for each potential adverse effect.

A client asks the nurse about starting polyethylene glycol (MiraLAX) for occasional constipation instead of a stimulant laxative. Which teaching point is accurate?

The nurse is comparing two clients with dyspepsia: one taking calcium carbonate regularly and one taking an aluminum-magnesium combination regularly. The nurse should recognize that a key difference in monitoring between these two clients relates to which bowel pattern?

The nurse is reviewing the medication list of a client who was just started on magnesium hydroxide (Milk of Magnesia) for constipation. Which pre-existing condition requires the nurse to notify the provider before administering this drug?