Please define PI3K in the following ways:a. As an enzymatic activity, mentioning the substrate and product.b. Molecular components.c. As a target of what kind(s) of oncogenic driver events?d. As a target of genomic driver events in specific cancers – Name 2 cancers for up to 2 total points, 1 point for each cancer accurately named.

Inactivates rods, activates cones

Question 1: Mechanotransduction and the Tumor Microenvironment Part A: Define “cellular mechanotransduction” and list three distinct examples of physical forces or mechanical signals that cancer cells may encounter in the physiological environment. Part B: In the context of the “Physical World” interacting with cell biology, explain how the extracellular matrix (ECM) changes during tumorigenesis compared to normal tissue. Part C: Describe the “feed-forward” loop described in the lecture regarding ECM stiffening. How does increased tissue tension affect cancer cell phenotype?

Order: Insulin sliding scale: If CBG 0-150 = 0 units151-200 = 2 units201-250 = 4 units251-300 = 6 units301-350 = 8 units 351- above = 10 units and call MDCBG is 342. How many units of insulin would you administer?

The _________ is the cost to a corporation of funds that it has generated, meaning it approximates the return that investors expect to earn on their equity investment.

Severed during split brain procedures (relates to structural lateralization of the brain).

The after-tax cost of debt will almost always be below

Second Normal Form eliminates:

Think about everything that you have learned over the course of the semester in this class.  Identify three concepts that you believe will benefit your career.  Why and how do you think these concepts will help you?  Explain your thoughts in detail.

Suppose a seller provides 10% off on all office supplies and an additional 20% off on a fountain pen. We know the original price of the fountain pen is $150, the end purchase price is $__[1]_____.