10.1. A 68-year-old woman presents with a slowly enlarging,…
10.1. A 68-year-old woman presents with a slowly enlarging, painless, broad-based, warty lesion involving the buccal mucosa and alveolar ridge. The lesion has been present for approximately 18 months. She has a long history of regular snuff use. There is no cervical lymphadenopathy.a) What is the most likely diagnosis? (1)b) State two (2) clinical features in this case that support your diagnosis. (2)c) What would you expect regarding the progression and spread of this lesion? (2)10.2. Briefly discuss the molecular pathogenesis of oral squamous cell carcinoma, highlighting key genetic and molecular alterations involved in tumour initiation and progression. (5)
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