The figure shows four cells, each suspended in a solution of…
The figure shows four cells, each suspended in a solution of water. The cells are permeable to water but not solutes. The internal and external concentrations of solutes for each cell are labeled. For which two cells will the net diffusion of water be into the cell? Select all that apply.
Read DetailsUse the genetic code in the table below to answer the follow…
Use the genetic code in the table below to answer the following question. The figure below shows a sequence of nitrogenous bases in the coding region of a gene, as well as the sequences of mRNA and amino acids coded by the DNA. Imagine that a mutation in the template strand changed the 6th base from adenine (A) to thymine (T). This mutation is shown in red font below. Which sequence of amino acids would be produced by gene expression of the mutated DNA?
Read DetailsCortisol is a signaling molecule that regulates gene express…
Cortisol is a signaling molecule that regulates gene expression in the cells of a mammal. Cortisol enters a cell and binds to a protein called a cortisol receptor. Binding of cortisol facilitates the phosphorylation of the cortisol receptor, which then can enter the nucleus and affect transcription. The figure shows a system of two genes whose transcription is regulated by cortisol: IL10 and BGLAP. The IL10 gene codes for a protein called interleukin 10. The BGLAP gene codes for a protein called osteocalcin. A cortisol receptor can activate or repress the transcription of a gene, depending on the structure of the gene’s regulatory element. For example, a cortisol receptor activates transcription of the IL10 gene but represses transcription of the BGLAP gene. A researcher removed these genes from cells and placed them in chemical solutions with specific concentrations of cortisol. All solutions contained high concentrations of the cortisol receptor and RNA polymerase. The next figure shows the data resulting from the experiment. Each graph shows the relative abundance of mRNA in the presence or absence of cortisol. The graph on the left shows the effect of cortisol on the expression of the IL10 gene. The graph on the right shows the effect of cortisol on the expression of the BGLAP gene. The researcher repeated the experiment with genes that contain a mutation. The last figure shows the results of this new experiment. Which region contains the mutation?
Read DetailsThe figure shows the movements of hydrogen ions (H+), potass…
The figure shows the movements of hydrogen ions (H+), potassium ions (K+), sucrose molecules, and calcium ions (Ca2+) through a cell membrane. The relative concentrations of each ion (high or low) are provided. From left to right, the proteins are labeled A, B, C and D. What type of protein is protein A?
Read DetailsMuscle cells require calcium ions (Ca2+) to contract. When t…
Muscle cells require calcium ions (Ca2+) to contract. When the concentration of calcium in the intracellular fluid decreases, a muscle cell relaxes. When the concentration of calcium in the cytoplasm increases, a muscle cell contracts. To prevent unwanted contraction, a muscle cell stores most of its Ca2+ in a specialized compartment within the cell, called an organelle. An organelle has its own membrane, similar in structure to the membrane that surrounds the cell. The concentration of Ca2+ in the intracellular fluid depends on the activity of transport proteins in the cell’s membrane and organelle’s membrane. The figures show a system of transport proteins that regulate the movement of Ca2+ in a cell. The top figure illustrates the function of the transport proteins in this system. The lower left-hand portion of the bottom figure shows a muscle cell as the concentration of calcium in the intracellular fluid decreases, leading to relaxation. The lower right-hand portion of the bottom figure shows a muscle cell as the concentration of calcium in the intracellular fluid increases, leading to contraction. Which word or phrase accurately completes the following sentence? If the concentration of sodium ions (Na+) outside of a muscle cell increases, the rate at which calcium ions (Ca2+) are transported out of this cell would _______.
Read DetailsThyroxine (T4) is a hormone that certain animals use to regu…
Thyroxine (T4) is a hormone that certain animals use to regulate the activity of cells. The production of T4 depends on the concentrations of two other hormones: thyrotropin releasing hormone (TRH) and thyroid stimulating hormone (TSH). TRH comes from a part of the brain called the hypothalamus. This hormone can bind to receptors in another part of the brain, called the pituitary gland. Upon binding to a receptor, TRH activates a signaling pathway that causes a cell to release TSH. The figure shows the signaling pathway that controls the production of T4. TSH binds to receptors in the thyroid gland, causing cells of this gland to produce T4. The production of T4 depends on an enzyme called thyroid peroxidase (TPO), which creates T4 by adding an iodide ion (I-) to a molecule. A nonpolar structure enables T4 to diffuse through the phospholipid bilayer of any cell, including cells of the hypothalamus and the pituitary gland, where T4 inhibits the release of TRH and TSH, respectively. About 1 in 200 people have a genetic condition called Graves’ disease. A person with this condition produces an excess of proteins that bind to TSH receptors, activating more of these receptors than usual. The next figure shows four hypothetical relationships between the number of TSH receptors activated by proteins and the concentration of T4 in a cell, labeled A through D. Which relationship accurately describes the expected relationship in a patient with Graves’ disease?
Read DetailsAn organism must regulate the concentration of solutes in it…
An organism must regulate the concentration of solutes in its body fluids, called osmolarity. An extreme change in osmolarity will alter the diffusion of water through cell membranes, potentially disrupting the functions of cells. In a healthy human, a homeostatic system ensures that the osmolarity of blood stays within a certain range. When the osmolarity increases, nerve cells in the hypothalamus detect the diffusion of water through channel proteins in their membranes (osmosis). These channels activate a signaling pathway that causes a nerve cell to secrete a hormone called vasopressin. A molecule of vasopressin can bind to receptors in the membranes of kidney cells, causing the kidneys to excrete less water as urine. Over time, the osmolarity of blood returns back to its expected range. Alcohol inhibits the release of vasopressin by nerve cells. Typically, a person who has not consumed alcohol has a concentration of vasopressin between 0.5 pg ml-1 and 2 pg ml-1, but a person who has ingested alcohol has a much lower concentration of vasopressin. The figure shows a path model of the homeostatic system that regulates the osmolarity of blood. This model also describes the effect of alcohol on the concentration of vasopressin in blood. The regulated variable is represented by a dashed box. Other variables are represented by a solid black box. An arrow connecting one box to another indicates a relationship between two variables. The value above each arrow indicates the slope of the linear relationship between the variables connected by the arrow. If the concentration of alcohol in the blood was 35 mmol L-1, how would the concentration of vasopressin in the blood change? The concentration of vasopressin would ______.
Read DetailsThe figure shows the movements of hydrogen ions (H+), potass…
The figure shows the movements of hydrogen ions (H+), potassium ions (K+), sucrose molecules, and calcium ions (Ca2+) through a cell membrane. The relative concentrations of each ion (high or low) are provided. From left to right, the proteins are labeled A, B, C and D. Which protein is an antiporter?
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