A 19-year-old college student is prescribed Risperidone for…
A 19-year-old college student is prescribed Risperidone for the treatment of First Episode Psychosis. After three weeks of adherence, the patient reports a complete cessation of auditory hallucinations but complains of a “total inability to feel joy,” decreased motivation, and a flat emotional response. The PMHNP recognizes that while the medication is effectively blocking D2 receptors in the mesolimbic pathway to treat positive symptoms, it may also be impacting the brain’s “reward center.”Which neurotransmitter and pathway are primarily responsible for these new-onset symptoms of secondary anhedonia?
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