Pick ONE Prompt: 1. Explain how a chromosomal mutation can be evolutionarily beneficial in one context but detrimental in another. 2. Define nondisjunction and explain how meiosis I nondisjunction differs from meiosis II nondisjunction in terms of gamete outcomes.

Which enzyme synthesizes small segments of RNA, which act as “hooks” for the new DNA strand to be elongated?

Pick ONE of the following essay prompts and thoroughly respond to it using complete sentences.Prompt 1: Answer the three following questions:What is a nucleosome-free region?Where are they typically found in a genome?How are nucleosome-free regions thought to be functionally important?Prompt 2: Answer the following questions:What is alternative splicing?What is its biological significancewhy would it be advantageous to a cell/organism?Prompt 3: Answer the following questions:What is a CpG island?Where would you expect one to be located?How does methylation of CpG islands affect gene expression?

Pick ONE of the following prompts to answer: Prompt 1: Explain the end replication problem in eukaryotic DNA replication. Why does it occur, and how do cells overcome it? Response should include discussion of DNA replication directionality and leading/lagging strands issues and the specific enzyme engaged in the process to overcome it. Prompt 2: Differentiate between crossing over and sister chromatid exchange (SCE). Why does only one of these generate new allele combinations?

Francis Crick proposed the adaptor hypothesis, and later the adaptor was discovered to be ______.

Which level of genetics studies inheritance of traits across generations?

In genomic imprinting, erasure of DNA methylation occurs in the 

Which correctly describe the process of conjugation? Select all that apply.

With rare exceptions, a calico cat is likely to be female.

Meiosis II nondisjunction results in