Q61. A researcher is studying antibody diversity developing in B cells. They observe that during V(D)J recombination, the enzyme terminal deoxynucleotidyl transferase (TdT) adds non-templated nucleotides at the junctions between gene segments. In which region of the antibody heavy chain is this junctional diversity most likely to directly affect the amino acid sequence?

Q38. Endogenous antigens, such as the viral proteins formed within cells, are presented to CD8+ cytotoxic T cells via class MHC molecules. The MHC molecule visible to CD8+ T cells only has one variable chain. The variable chain needs another molecule to alter its conformation and help create a stable groove between its α1α2 domains. Without stabilization of the variable domain, viral peptides could not load onto the grove formed by the α1α2 component of the variable chain. Which molecule adjusts the 3-D structure of the variable chain of the MHC molecule visible to CD8+ T cells?  

On average, what percent of genes do we share with our grandparents? 

If you plot out the heights of a population of adults, we would expect to get a bell-shaped curve. Based on this distribution alone, answer the following two questions:  What kind of trait is height? [blank1] Is height consistent with an additive, threshold, or other type of model? [blank2]

Which of the following  is part of a ‘precision medicine’ approach to cancer?

Please describe X-chromosome inactivation. Make sure your brief response covers the following elements. Brief phrases are fine.  a. What is it? b. When does it occur? c. How does it occur (ie, what is the process or mechanism)? d. What is thought to be the purpose of X-chromosome inactivation?  

How can a non-coding RNA act as an epigenetic mechanism?

The nurse administering donepezil (Aricept) to a patient with Alzheimer’s disease understands this drug has which expected therapeutic action?

The nurse is evaluating a patient with muscle weakness who received edrophonium, also known as the tensilon test.  After injection, the patient shows improved muscle strength.  The nurse knows this response of improved muscle strength to edrophonium is consistent with which of the following diseases?  

What will the nurse teach their client about taking corticosteroids?  Select all that apply.