Combining meglitinides and sulfonylureas can cause:    excessive insulin secretion.   excessive weight loss.   increased risk of pancreatitis.   increased renal clearance. 

Which drug class has been shown to reduce the risk of major cardiovascular events in patients with diabetes?   Meglitinides   Sulfonylureas   Alpha-glucosidase inhibitors   SGLT2 inhibitors 

What is a common adverse effect of medroxyprogesterone acetate injections?  Hypotension   Bone loss   Hyperkalemia   Acne 

What is a major adverse effect of thiazolidinediones?   Vitamin B12 deficiency   Fluid retention   GI intolerance   Hypoglycemia 

Which adverse effect is most common with metformin?   Hypoglycemia   Hyperinsulinemia   GI upset   Weight gain 

How does metformin primarily work?   Reduces hepatic gluconeogenesis   Delays gastric emptying   Inhibits alpha-glucosidase   Stimulates insulin secretion 

What adverse effect is associated with SGLT2 inhibitors?  Thyroid cancer   Hyperkalemia   Hypoglycemia   Genital mycotic infections 

What is a unique benefit of SGLT2 inhibitors?   Increased beta-cell proliferation   Suppression of glucagon release   Reduction in cardiovascular and renal events   Delayed carbohydrate absorption 

Inhaled anticholinergic medications improve airflow in patients with COPD through which primary mechanism?   Increasing surfactant production to improve alveolar expansion   Inhibiting leukotriene synthesis to decrease airway inflammation   Stimulating beta-2 receptors to directly relax bronchial smooth muscle   Blocking muscarinic receptors in bronchial smooth muscle to reduce bronchoconstriction 

Which drug class stimulates insulin secretion by blocking ATP-sensitive K+ channels?   Thiazolidinediones   GLP-1 receptor agonists   SGLT2 inhibitors   Sulfonylureas