A 46-year-old woman has a urinary tract infection which has become a systemic infection with fever and lethargy. Nitrofurantoin, an effective urinary antiseptic, would not be recommend for her treatment because

A patient with type 2 diabetes is taking metformin.  The fasting glucose levels are in range, but the posprandial glucose is uncontrolled.  All of the following drugs would be appropriate to add to the metformin to target postprandial glucose except: 

Which of the following hypoglycemic agents have been associated with weight loss?

KD is a 63-year-old, 77-kg male with a history of diabetes mellitus type 2, hypertension, and end-stage renal disease. He is dependent on hemodialysis, and he receives dialysis every Monday, Wednesday, and Friday. Over the past 6 months, he has become more fatigued overall, and tires much more easily during his daily activities. Therapy was initiated with oral ferrous sulfate 325 mg 3 times daily, but KD’s symptoms have not improved. Over the last two weeks, his hemoglobin and hematocrit levels have been low, and he has required two blood transfusions (one each week) after the Wednesday dialysis sessions. His nephrologist is initiating erythropoietin 8000 units subcutaneously every Wednesday. Which factor(s) is (are) critical to consider prior to initiation of erythropoietin therapy? 

Which of the following statements are true.  Select all the apply.  

A 52-year-old man who suffers from angina when he climbs stairs or participates in similar activities receives a prescription for nitroglycerin (glyceryl trinitrate). He is instructed to take a tablet 1 or 2 minutes before he expects to climb stairs to prevent the angina. What is the mechanism of action of nitroglycerin that prevents angina from developing in this patient?

KD is a 63-year-old, 77-kg male with a history of diabetes mellitus type 2, hypertension, and end-stage renal disease. He is dependent on hemodialysis, and he receives dialysis every Monday, Wednesday, and Friday. Over the past 6 months, he has become more fatigued overall, and tires much more easily during his daily activities. Therapy was initiated with oral ferrous sulfate 325 mg 3 times daily, but KD’s symptoms have not improved. Over the last two weeks, his hemoglobin and hematocrit levels have been low, and he has required two blood transfusions (one each week) after the Wednesday dialysis sessions. His nephrologist is initiating erythropoietin 8000 units subcutaneously every Wednesday. Which factor(s) is (are) critical to consider prior to initiation of erythropoietin therapy? 

The occurrence of myopathy increases when statin doses of greater than 25% of the maximal dose are used with niacin. 

Which of the following medications should be discontinued in a woman with essential hypertension who is trying to get pregnant?  

ACE inhibitors and ARBs are first-line drugs used at all stages to prevent and slow the progression of heart failure by inhibiting the renin-angiotensin-aldosterone system.