Dinitrophenol (DNP) was once used as a diet pill but was fou…
Dinitrophenol (DNP) was once used as a diet pill but was found to be extremely dangerous. DNP is an uncoupler that dissipates the proton gradient across membranes, like the mitochondrial inner membrane. Why is DNP both effective as a diet pill and dangerous to those who take it?
Read DetailsScenario: Patient F presents deficits in social communicatio…
Scenario: Patient F presents deficits in social communication and interaction accompanied with restricted, repetitive behavior. Language impairment is also noted and he is receptive to language therapy in which he is learning to “use words” instead of his hands, when expressing what he wants or needs. A recent neurological exam demonstrates deficits in motivation, goal-directed behavior, social cognition and attention. Interestingly, results also indicate deficiencies within the pathways connecting the cerebellum and frontal cortex (e.g., cerebello-thalamic-cortical pathway). Which of the following most closely reflects the scenario
Read DetailsScenario: In 1995, Dr. E evaluated a 7 year-old patient, Pat…
Scenario: In 1995, Dr. E evaluated a 7 year-old patient, Patient D. The following was found: – Patient D has allergies and takes the antihistamine Benadryl. – Patient D presents emotion-based behavior, poor abstract thinking and deficits in logical reasoning. – Patient D is impulsive at times – Patient D requires constant reminding of what needs to be done. . Overall, Dr. E was reluctant in diagnosing Patient D with a neurodevelopmental disorder. Why?
Read DetailsScenario: Patient I presents resting tremor, rigidity, brady…
Scenario: Patient I presents resting tremor, rigidity, bradykinesia and postural imbalance. Specifically, his legs and hands shake when he sits and when he walks, his gait and posture are disturbed. He is currently prescribed Sinemet (levodopa/carbidopa). He frequently visits his doctor to make certain the dose is high enough to be effective but not too high, as this may result in the onset of psychosis. Which of the following most closely reflects the scenario
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