A 47-year-old with an inversion ankle sprain has normal radiographs and intact neurovascular exam. He requests opioids. What is the best approach?

A 60-year-old man has an acute onset of severe pain, redness, and swelling at the great toe joint after a large meal and alcohol. What is the most appropriate initial therapy?

A 55-year-old man has erectile difficulties for one year. He has hypertension and hyperlipidemia. Which initial evaluation step is most appropriate?

A 28-year-old with migraine history reports a sudden “worst headache of life,” different from prior attacks. What is the next best step?

A 31-year-old woman has unilateral painful vision loss and a relative afferent pupillary defect; she reports past transient neurologic episodes. Which diagnosis should be strongly considered?

A 58-year-old man has a painless scrotal swelling that transilluminates. He can feel the testis separate from the swelling. What is the most likely diagnosis?

A 64-year-old with knee osteoarthritis has posterior knee fullness and discomfort; ultrasound shows a popliteal cyst. He has no redness or severe pain. What is the best management?

A 72-year-old woman has new headache, scalp tenderness, jaw claudication, elevated inflammatory markers, and sudden visual changes. What is the most appropriate immediate management?

A 61-year-old woman with new-onset constipation and unintentional weight loss denies opioid use. What is the next best step?

A 59-year-old has brief, electric-shock facial pain triggered by chewing; neurologic exam is normal. What is the first-line medication?