Match correctly with the option that means the same or expresses  direct consequence

Miranda Rights.  Complete the Miranda Rights with the correct words and translate those words in English. Number your answers. Choose from: abogado (2x) – hablar – silencio – diga – comprende – justicia – derecho (2x)  – contra Tiene __________(1) a permanecer en ____________(2) Cualquier cosa que _________(3) puede ser usada en su __________(4) en un tribunal de ______________(5). Tiene ____________(6) a un ____________ (7) durante el interrogatorio. Si no puede pagar un ___________(8), se le asignará uno. ¿ _________________ (9) los derechos que le acabo de leer? Teniendo estos derechos en cuenta, ¿ desea ____________(10) conmigo?

Which type of enzyme inhibitor “prepays” the entropic cost of binding substrates?  

Consider the following reaction catalyzed by an esterase that is a therapeutic target. Which of the reaction species above (0 through 3) is likely to have the most energetically favorable interactions with amino acids in the enzyme active site?                

                   Which of the following is the product of the reaction above?               

Which of the following phenols is the strongest acid?                    

4)  What is the best explanation for the relative Kd values of molecules 1-3?

para-fluorophenol will have a pKa that is higher or lower than phenol?

Rational drug design relies on what kind of information or materials for success?

The esterase below is a therapeutic target for inhibition              Which of the following molecules is a potential mechanism based inhibitor of this enzyme?