The following DNA fragment is from the middle of the protein…
The following DNA fragment is from the middle of the protein-coding sequence of a gene. CACTCTGTTCCCGGTAGTGAGACAAGGGCCATYou determine that the sequence contains a tryptophan codon. Use that information to label the 5’ and 3’ ends of both strands of the above sequence.5′ end is: (write top or bottom)3′ end is: (write top or bottom) Write out the sequence of the mRNA produced from this bit of DNA. Write from 3′ to 5′ direction. A mutation happens that affects a single base-pair, and changes the fourth amino acid (read NH2 to COOH) to phenylalanine (Phe). It doesn’t affect any other amino acids. 3′ CACTCTGTTCCTGGTA 5′ 5′ GTGAGACAAGGACCAT 3′ What type of mutation is it?
Read DetailsA mammalian genome has been sequenced and shown to have the…
A mammalian genome has been sequenced and shown to have the genomic DNA arrangement at its antibody light chain locus shown below. Imagine that it undergoes recombination to join V4 to J3. How many different light chains can be produced from this gene? (Consider only recombination).
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