What is the MOST important factor when considering the onset of action of local anesthetics?

Match the following local anesthetics with their appropriate drug class:

Please choose all that apply to Local Anesthetic Systemic Toxicity (LAST):

Please match the following local anesthetics with their pKa:

Most local anesthetics have a biphasic effect on blood vessels. This means at low doses they ___________ vessels and at higher doses they __________ vessels.

Consider the injection of local anesthetic into the following tissues. Please number them according to highest (1) to least (6) blood concentration based on the site:

Which of the following would decrease the rate of rise of a volatile anesthetic? (Please select all that apply.)

In the lab you observe large, fat cells.  How would you describe the solution around the cell?  Remember that water follows salt.

Isolationism advocates a nation actively engaging in foreign entanglements.

Foreign Policy refers to a government’s strategy in dealing with domestic issues.