Label each of the following changes as:  i) a synonymous mutation, ii) a non-synonymous substitution, iii) a stop-loss mutation, iv) a nonsense (stop-gain) mutation. (A genetic code table is below).   A) UGA –> UCA [A]  B) UAC –> UAA [B]  C) AGA –> AAA [C]  D) AGA –> CGA [D]   

DM 3 You are determined to find the D&M gene.  The markers above allow you to localize the D&M gene to a small region of chromosome 7.  How would you now proceed to identify the D&M gene and verify that variants within the D&M gene are responsible for the disease? 

I am aware of the electronic monitoring process: I will have to have a camera, and show my id and scan the room.  Additionally, I am aware that I will only have one chance to answer each question in the order they appear, and that I will not be able to go back and review questions a second time. Good luck and don’t forget to download the study material (:

In an siRNA knockdown experiment described in the lecture, the siRNA knockdown of Per1 led to a change in expression of target kidney genes.  In that experiment, why was the scramble siRNA an important control?

Some members of the Baby Boomer Generation are struggling financially because:

Which generation are the ones you want more “purpose in life”, and want a work/life balance?

•Life-course theories are created by analyzing the behaviours of ___________________  of _______________ over a long period of time.   Think about who you would study!

Identity vs. Role Confusion happens when a person is about to turn 40. This is also known as a “midlife crisis”.

Indicate the type of measurement based on the indicated unit.  Use the dropdown menu to choose the correct unit. 

Mathew Giardino spoke about KPIs, what does that stand for?