Are the infected strain A cells killed or not killed?  Explain.

Where will a B cell more than likely encounter antigen and go through class switching?

Spleen cells are taken from a mouse immunized with the LCM virus.  2 assays are used to determine antigen-specific functional activity of the spleen cells.   Assay 1: the spleen cells (T cells) are incubated with macrophages that have been briefly exposed to LCM virus (phagocytized the virus), production of IL-2 by the T cells is considered a positive response. Assay 2: the spleen cells are incubated with LCM-infected target cells, lysis of the infected target cells is considered a positive response. The functional activity of which MHC molecules is detected in Assay 1?

During T cell development, what does it mean when the thymocyte is double positive?

Taking into account the selection process of developing T cells in the thymus, why would somatic hypermutation in the genes of the TCR not be beneficial (remember that somatic hypermutation in the B cell antibody gene can take place after gene rearrangement and expression) to an individual and could lead to problems?

Name 4 of the 7 ways antibody diversity is generated. 

Spleen cells are taken from a mouse immunized with the LCM virus.  2 assays are used to determine antigen-specific functional activity of the spleen cells.   Assay 1: the spleen cells (T cells) are incubated with macrophages that have been briefly exposed to LCM virus (phagocytized the virus), production of IL-2 by the T cells is considered a positive response. Assay 2: the spleen cells are incubated with LCM-infected target cells, lysis of the infected target cells is considered a positive response. Activity of which cell population is detected in Assay 2?

What is the difference between a primary immunodeficiency and acquired immunodeficiency?

What is a cytokine?

Do you inherit immunological memory?  What cells types are responsible for immunological memory?