Most individuals with genetic defects in oxidative phosphory…
Most individuals with genetic defects in oxidative phosphorylation have relatively high concentrations of alanine in their blood. Complete the passage to explain this phenomenon in biochemical terms. Citric acid cycle activity [box1] because NADH cannot transfer electrons to oxygen. However, glycolysis continues to produce [box2]. because [box3], cannot enter the cycle, [box4] converts the accumulating glycolysis product to alanine, resulting in elevated alanine concentrations in the tissues and blood.
Read DetailsFor each pair of biomolecules, identify the type of reaction…
For each pair of biomolecules, identify the type of reaction (oxidation‑reduction, hydrolysis, isomerization, group transfer, or internal rearrangement) required to convert the first molecule to the second. In each case, indicate the general type of enzyme and cofactor(s) or reactants required, and any other products that would result. A(n) [box1] reaction converts L-leucine to D-leucine. The reaction is catalyzed by a(n) [box2].
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