Link for the Exam problems: Exam 1 Link for the Birth Data file: Birth Data

In a generalized linear model, the probability of a neural response is dependent on the statistics of the stimulus, in addition to those governing the neuron’s intrinsic mechanisms (its firing history)

In molluscan neurons, the carrier of inward current during the rising phase of the action potential is usually calcium.  This ion has an unusually steep concentration gradient.  Given the values below, what is the equilibrium potential for Ca2+ at 20 deg Celsius?   (Consider the options carefully.) [Ca2+]o = 10-2 M          [Ca2+]i = 1.7 x 10-7 M                [Ca2+]o  log ——— = 4.77        [Ca2+]i          [Ca2+]i  log ——— = -4.77        [Ca2+]o

The voltage clamp permits the experimenter to “clamp” the membrane current at predetermined levels, preventing changes in membrane voltage from influencing the membrane current. By controlling the membrane current one can measure the effect of changes in membrane current on the membrane’s conductance of individual ion species.

The crosscorrelation function of two neurons’ spike trains tells us something about

The time constant of synaptic integration of a Leaky Integrate and Fire neuron will affect the coefficient of variation in the following ways

The central idea of projecting the neural data onto a lower dimensional space (e.g. principal component analysis) is to reduce the dimensionality of a data set consisting of a large number of interrelated variables, while retaining as much as possible of the variation present that could be attributed to the stimulus that evoked this neural activity.

Certain features of single neuron firing violate the independent spike hypothesis of a Poisson neuron. Among these features (check all that apply):

In the Kalman filter,

The discriminability index in hypothesis testing provides a complete characterization of the decoding of a signal assuming that the noise follows a normal (Gaussian) distribution with a fixed variance, independent of the signal strength In the graphs below, different signal detection thresholds are shown. Check all that apply: A     B     C