A 24-year-old male presents to his primary care physician fo…
A 24-year-old male presents to his primary care physician for evaluation of recurrent fever, night sweats, and weight loss. The patient reports that he has been experiencing these symptoms for the past several weeks. After a complete physical exam and a series of laboratory and diagnostic tests, the patient undergoes an excisional lymph node biopsy (see image). He is determined to have Stage IIB disease. Which of the following clinical findings would be an adverse prognostic factor in this patient?
Read DetailsA patient develops fever, chills, and back pain shortly afte…
A patient develops fever, chills, and back pain shortly after starting a blood transfusion. Laboratory tests show an increase in bilirubin and a decrease in haptoglobin levels. Which of the following is the most appropriate diagnostic test to confirm an acute hemolytic transfusion reaction?
Read DetailsA 25-year-old female presents to her primary care provider f…
A 25-year-old female presents to her primary care provider for evaluation of fatigue which has persisted for the past 6 months. She has tried multiple diets and sleep schedules to improve her condition, but none have succeeded. She has no significant past medical history. She is currently taking a multivitamin daily. Vital signs: T: 98.8°F (37.1°C), BP: 107/58 mmHg, HR: 90/min, RR: 13/min, and oxygen saturation is 98% on room air. Laboratory values are seen below. Hemoglobin: 8 g/dL Hematocrit: 24% MCV: 118 Leukocyte count: 6,500 with normal differentialPlatelet count: 147,000 Physical exam is notable for decreased proprioception in the lower extremities. Which of the following is the most appropriate next step in management to confirm the diagnosis?
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