GIVEN: Normal hemoglobin is a tetramer, consisting of two po…
GIVEN: Normal hemoglobin is a tetramer, consisting of two polpeptides of beta hemoglobin and two polypeptides of alpha hemoglobin. In sickle-cell disease, as a result of a single amino acid change, the mutant hemoglobin tetramers associate with each other and assemble into large fibers. Based on this information alone, we can conclude that sickle-cell hemoglobin exhibits
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