Sickle-cell anemia is a genetic disease involving a single g…
Sickle-cell anemia is a genetic disease involving a single gene. Normal homozygous (SS) have normal blood, these individuals become very ill from the malaria parasite and many die. Individuals homozygous for the sickle-cell trait (ss) individuals often die because of the genetic defect. Individuals with the heterozygous condition (Ss) have some sickling of red blood cells, but generally not enough to cause mortality. In addition, malaria cannot survive well within these “partially defective” red blood cells thus, heterozygotes tend to survive. If 9% of an African population is born with a severe form of sickle-cell anemia, what proportion of the population is likely to become very ill from the malaria parasite?
Read DetailsSickle-cell anemia is a genetic disease involving a single g…
Sickle-cell anemia is a genetic disease involving a single gene. Normal homozygous (SS) have normal blood, these individuals become very ill from the malaria parasite and many die. Individuals homozygous for the sickle-cell trait (ss) individuals often die because of the genetic defect. Individuals with the heterozygous condition (Ss) have some sickling of red blood cells, but generally not enough to cause mortality. In addition, malaria cannot survive well within these “partially defective” red blood cells thus, heterozygotes tend to survive. If 9% of an African population is born with a severe form of sickle-cell anemia, what proportion of the population is likely to become very ill from the malaria parasite?
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