The practice pharmacist reviews the repeat prescription for edoxaban. Mrs. JN (78 years old) weighs 65kg and her serum creatinine is 105micomol/l. What dose of edoxaban would be MOST APPROPRIATE for Mrs. JN.

The microbiologist rings the ward and recommends that intravenous (IV) liposomal amphotericin B 3mg/kg is prescribed for Ms. JJ (60kg) for aspergillosis. Which prescription would be the most appropriate?

Miss ST requires surgery and is started on a variable rate insulin infusion. Which statement is NOT CORRECT?

Baby L (5kg) is prescribed furosemide solution 1mg/kg twice a day. Furosemide Oral Solution (20mg/5mL and 50mg/5mL) contains 8% w/v ethanol. Assuming that the maximum dose threshold for ethanol in children is 15mg/kg/dose, which prescription would be MOST APPROPRIATE for baby L?

A patient is dispensed amiloride instead of amlodipine from a pharmacy. The error is identified before the patient takes the medication, but it raises concerns about the potential consequences of the mistake. The pharmacy team decide to conduct a root cause analysis (RCA) to understand why the error occurred. Which would NOT be a potential step in the RCA process?

Mr. FG develops constricted pupils, becomes unresponsive and has a reduced respiratory rate. Which situation WOULD NOT contribute to the development of these symptoms?

Which would be the MOST EFFECTIVE barrier to prevent the same incident happening again?

Mrs. JN is quite concerned about the risk of bleeding and asks whether edoxaban has a reversal agent. Which statement is CORRECT?

What is the MOST APPROPRIATE initial course of action?

Whilst recording the error, you are required to define the level of harm to the patient. Which harm grading applies to this patient safety event?