John, a 38-year-old male with MDD and GAD, has been on sertraline 100 mg daily for 8 weeks. His depressive symptoms have moderately improved, but he reports persistent restlessness, excessive worry, and difficulty sleeping. He also complains of new-onset sexual dysfunction, which is straining his relationship. What is the best pharmacological adjustment?

Karen, a 58-year-old female with treatment-resistant depression, has failed trials of multiple SSRIs, SNRIs, and atypical antidepressants. She is reluctant to undergo ECT but is open to alternative treatments. Which treatment option should be considered next?

What is meant by the pelvic-femoral rhythm? Provide one example.

Which of the following principles applies to adverse medication reactions in the elderly?

Jason is a 40-year-old man with treatment-resistant depression. He has tried sertraline, bupropion, and venlafaxine without significant improvement. He reports no history of mania or psychotic symptoms. Which augmentation strategy should the PMHNP consider?

Bupropion is an atypical antidepressant that is unique because it primarily:

Emily, a 28-year-old female, was started on duloxetine 30 mg daily for MDD and GAD. After 4 weeks, her anxiety symptoms have improved, but she complains of persistent nausea and intermittent diarrhea. How should her medication regimen be adjusted?

(MC) The Soviet Union held its first successful atomic test on August 29, 1949. What impact did this have on the United States? (2 points)

Identify the muscles in the figure. There are 4: A-D.

Which level of protein structure contains an alpha helix and beta pleated sheets?