A 74-year-old female with hypertension presents with confusi…
A 74-year-old female with hypertension presents with confusion and a sodium level of 118 mEq/L. She recently underwent hip surgery and has been receiving morphine. Urine is concentrated, and serum osmolality is low. What is the most likely cause of her hyponatremia?
Read DetailsA 63-year-old male presents with progressive fatigue, weight…
A 63-year-old male presents with progressive fatigue, weight loss, and vague abdominal discomfort. Imaging reveals hepatosplenomegaly and lymphadenopathy. A biopsy confirms chronic lymphocytic leukemia (CLL). What cellular characteristic best explains this diagnosis?
Read DetailsA 22-year-old patient who weighs 62kg is admitted to hospita…
A 22-year-old patient who weighs 62kg is admitted to hospital after taking an overdose of propranolol tablets. She admits to taking 28 propranolol 40mg tablets. The patient is prescribed intravenous glucagon and given an initial bolus of 10mg over 10 minutes. Following the bolus, she is prescribed an intravenous infusion at a dose of 50microgram/kg/hour for 60 minutes. The glucagon solution used for the infusion is prepared at a concentration of 1mg/mL. How many milligrams of the glucagon will the patient receive in total Give your answer to ONE (1) decimal place.
Read DetailsA 13-year-old patient is prescribed IV clarithromycin 500mg…
A 13-year-old patient is prescribed IV clarithromycin 500mg BD. He weighs 44kg, is 135cm tall and has a recent serum creatinine of 128 micromol/L. The equation to calculate eGFR in paediatric patients is provided below: eGFR (mL/minute/1.73m2) = height (cm) x 40 / serum creatinine (micromol/L) The usual dose of clarithromycin is reduced by 50% if the eGFR is between 10-50 mL/minute/1.73m2 and by 75% if the eGFR is less than 10 mL/minute/1.73m2. How many milligrams of clarithromycin should be prescribed for this patient per dose?
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