A cell responds to two types of signaling molecules. Estroge…
A cell responds to two types of signaling molecules. Estrogen is a signaling molecule that binds to an intracellular receptor known as an estrogen receptor (ER), ultimately causing gene expression. Insulin-like growth factor 1 (IGF-1) is a signaling molecule that binds to a membrane receptor (IGF-1R). Upon binding to IGF-1R, a molecule of IGF-1 activates a signaling pathway that can phosphorylate ER, enhancing the rate of gene expression caused by estrogen alone. The figure shows the integration of the two signaling pathways. Which condition would most likely cause the highest rate of gene expression?
Read DetailsA cell responds to two types of signaling molecules. Estroge…
A cell responds to two types of signaling molecules. Estrogen is a signaling molecule that binds to an intracellular receptor known as an estrogen receptor (ER), ultimately causing gene expression. Insulin-like growth factor 1 (IGF-1) is a signaling molecule that binds to a membrane receptor (IGF-1R). Upon binding to IGF-1R, a molecule of IGF-1 activates a signaling pathway that can phosphorylate ER, enhancing the rate of gene expression caused by estrogen alone. The figure shows the integration of the two signaling pathways. Which cellular responses should occur in the presence of estrogen and absence of IGF-1? Select all that apply.
Read DetailsThe top figure shows four signaling pathways, labeled 1 thro…
The top figure shows four signaling pathways, labeled 1 through 4. All pathways begin with the same receptor being triggered by the same signaling molecule. However, the secondary messengers that follow are ordered differently among the pathways. The bottom figure shows a relationship between the presence or absence of an activated protein W and the activity of protein Y. Which signaling pathways are consistent with the data presented in the bottom figure? Select all that apply.
Read DetailsThe top figure shows four signaling pathways, labeled 1 thro…
The top figure shows four signaling pathways, labeled 1 through 4. All pathways begin with the same receptor being triggered by the same signaling molecule. However, the secondary messengers that follow are ordered differently among the pathways. The bottom figure shows a relationship between the presence or absence of an activated protein X and the activity of protein W. Which signaling pathways are consistent with the data presented in the bottom figure? Select all that apply.
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