A 5-year-old girl becomes very ill after a bacterial infecti…
A 5-year-old girl becomes very ill after a bacterial infection. She was found to have toxic shock due to exposure to bacterial superantigens. Superantigens are different from regular antigens in that they stimulate many T cells. This excessive stimulation is accomplished by antigen binding outside of the normal MHC class II cleft presentation. Superantigens act by binding MHC Class II on APCs to which of the following receptors on T cells?
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